Single Enantiomer Epoxides by Bromomandelation of Prochiral Alkenes
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چکیده
منابع مشابه
Single enantiomer epoxides by bromomandelation of prochiral alkenes.
A combination of mandelic acid and N-bromosuccinimide efficiently converts prochiral alkenes into a readily separable 1:1 mixture of the bromomandelates. The diastereomerically pure bromomandelates are then converted into a variety of enantiomerically pure products. Terminal alkenes are converted into enantiomerically pure epoxides. Cyclohexene is converted into enantiomerically pure cis-2-azid...
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ژورنال
عنوان ژورنال: The Journal of Organic Chemistry
سال: 2006
ISSN: 0022-3263,1520-6904
DOI: 10.1021/jo061818r